Medicinal Mushrooms
Chaga Mushroom
Also known as: Inonotus obliquus · Black mass · Clinker polypore
A parasitic fungus from birch trees with one of the highest ORAC scores of any natural substance. Significant antioxidant and immune-modulating activity, but human clinical trials are limited.
Effective Dose
1000–2000mg / day
per clinical evidence
Evidence Level
Limited
Medicinal Mushrooms
Mechanism
Beta-glucan immune modulation, superoxide dismutase antioxidant activity
primary action
Best For
Antioxidant protection
Immune health, Inflammation
This profile is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications.
What Is Chaga Mushroom?
Chaga is a sclerotium (hard mass of fungal mycelium) that grows on birch trees in cold climates. Its black outer layer is loaded with melanin and betulinic acid (from the birch bark), while the inner mass contains polysaccharides and superoxide dismutase (SOD). Human clinical evidence is emerging, with most data from in-vitro and animal studies.
How It Works: The Science
Chaga polysaccharides activate macrophages and NK cells via Dectin-1 and TLR-2 receptors. Betulinic acid has anti-inflammatory and potential antitumour effects via TRAIL pathway activation. SOD-like compounds quench superoxide radicals. Melanin pigments chelate free radicals and UV radiation.
Primary Mechanism
Beta-glucan immune modulation, superoxide dismutase antioxidant activity
Evidence-Based Benefits
Dosage Guide
Effective Dose
1000–2000mg / day
1000–2000mg powder or extract daily. Hot water extraction is necessary for beta-glucan bioavailability — raw powder is less effective. Teas and dual extracts preferred.
Safety Profile & Side Effects
Generally safe. Contains high amounts of oxalates — may contribute to kidney stone risk with chronic high-dose use. Caution if prone to kidney stones.
Who Should (and Shouldn't) Take It
Those interested in antioxidant support and immune resilience, particularly those in cold climates or with chronic inflammation. Evidence is promising but less robust than lion's mane or reishi.
Frequently Asked Questions
Related Ingredients
Medical Disclaimer
Ingredient profiles are for informational purposes only and do not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications. Full disclaimer →