Raspberry Ketones

○○○Insufficient Data

Highly marketed but essentially unproven in humans. Only one mouse study and no human RCT demonstrating fat loss. Not recommended over proven alternatives.

Effective Dose

100–400mg / day

per clinical evidence

Evidence Level

Insufficient

Weight Management

Mechanism

Adiponectin elevation (proposed), norepinephrine sensitisation

primary action

Best For

—

This profile is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications.

What Is Raspberry Ketones?

Raspberry ketones are aromatic compounds responsible for the scent of raspberries. They are structurally similar to synephrine and capsaicin. Animal studies show elevated adiponectin and reduced fat accumulation, but the doses used in mouse studies are 100–1000× what is achievable with human supplements.

How It Works: The Science

Proposed mechanism: raspberry ketones stimulate adiponectin secretion from adipocytes. Adiponectin enhances insulin sensitivity and fat oxidation. However, the concentrations required to demonstrate these effects in cell and animal studies exceed achievable human plasma concentrations by several orders of magnitude.

Primary Mechanism

Adiponectin elevation (proposed), norepinephrine sensitisation

Evidence-Based Benefits

No human RCT evidence for fat loss

insufficient

Park (2010) — mouse study only; human equivalence not established

Dosage Guide

Effective Dose

100–400mg / day

Not recommended. If using: 100–400mg/day. Evidence base does not support this ingredient.

Safety Profile & Side Effects

Generally safe at supplemental doses. Not toxic. Simply not proven to work.

Who Should (and Shouldn't) Take It

Best for

Who it's for

Not recommended. Budget is better spent on evidenced ingredients (caffeine, EGCG, glucomannan, protein).

Frequently Asked Questions

What is the recommended dose of Raspberry Ketones?

Not recommended. If using: 100–400mg/day. Evidence base does not support this ingredient.

Is Raspberry Ketones safe?

Generally safe at supplemental doses. Not toxic. Simply not proven to work.

How does Raspberry Ketones work?

Who should take Raspberry Ketones?

Not recommended. Budget is better spent on evidenced ingredients (caffeine, EGCG, glucomannan, protein).

Related Ingredients

Green Tea Extract (EGCG)Synephrine (Bitter Orange Extract)Capsaicin (Capsaicinoids)

Medical Disclaimer

Ingredient profiles are for informational purposes only and do not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications. Full disclaimer →