ING-059Ingredient Research Profile

Adaptogens

Holy Basil (Tulsi)

Also known as: Ocimum sanctum · Ocimum tenuiflorum · Tulsi

●●○Moderate Evidence

A sacred Ayurvedic herb with consistent evidence for stress reduction, blood glucose control, and mild anti-inflammatory effects. Eugenol and ursolic acid are the key actives.

Effective Dose

300–600mg / day

per clinical evidence

Evidence Level

Moderate

Adaptogens

Mechanism

COX-2 inhibition, cortisol modulation, HPA axis support

primary action

Best For

Stress

Blood sugar, Inflammation, Cognitive clarity

This profile is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications.

What Is Holy Basil (Tulsi)?

Holy basil (Tulsi) holds sacred status in Hinduism and has been used medicinally in USA for thousands of years. Modern research confirms its adaptogenic properties — it reduces cortisol, stabilises blood glucose, and modulates inflammatory pathways. It is distinct from culinary basil (Ocimum basilicum).

How It Works: The Science

Eugenol (a phenylpropanoid) inhibits COX-2 (anti-inflammatory), ursolic acid inhibits NF-κB, and rosmarinic acid scavenges free radicals. Together these actives reduce the physiological stress response, stabilise blood glucose via alpha-glucosidase inhibition, and reduce systemic inflammation.

Primary Mechanism

COX-2 inhibition, cortisol modulation, HPA axis support

Evidence-Based Benefits

Reduces anxiety and stress perception

moderate

Bhattacharyya et al. (2008) — significant anxiety reduction vs placebo over 60 days

Lowers fasting blood glucose in type 2 diabetes

moderate

Agrawal et al. (1996) — 17.6% reduction in fasting glucose

Reduces inflammatory markers

moderate

Rai et al. (1997) — reduced pain and disability in arthritis patients

Dosage Guide

Effective Dose

300–600mg / day

300–600mg standardised extract (2.5% ursolic acid) twice daily. Available as capsules, powder, or traditional tea (fresh or dried leaves).

Safety Profile & Side Effects

Very safe as a food-grade herb. May have mild blood thinning properties — caution with anticoagulants. Theoretical concerns about fertility with very high doses (animal data only).

Who Should (and Shouldn't) Take It

Best for

StressBlood sugarInflammationCognitive clarity

Who it's for

Those with stress, mild blood sugar dysregulation, or chronic low-grade inflammation. A gentle, well-tolerated adaptogen ideal for daily use.

Frequently Asked Questions

What is the recommended dose of Holy Basil (Tulsi)?

300–600mg standardised extract (2.5% ursolic acid) twice daily. Available as capsules, powder, or traditional tea (fresh or dried leaves).

Is Holy Basil (Tulsi) safe?

Very safe as a food-grade herb. May have mild blood thinning properties — caution with anticoagulants. Theoretical concerns about fertility with very high doses (animal data only).

How does Holy Basil (Tulsi) work?

Who should take Holy Basil (Tulsi)?

Those with stress, mild blood sugar dysregulation, or chronic low-grade inflammation. A gentle, well-tolerated adaptogen ideal for daily use.

Related Ingredients

Ashwagandha (KSM-66 / Sensoril)Rhodiola Rosea Berberine

Medical Disclaimer

Ingredient profiles are for informational purposes only and do not constitute medical advice. Consult a qualified healthcare professional before starting any supplementation, especially if you have pre-existing conditions or take medications. Full disclaimer →